Due to challenges of addiction, abuse, and misuse with opioids, even at recommended doses [see Warnings and Safety measures (5.1)], reserve promethazine HCl and codeine phosphate oral Remedy to be used in Grownup individuals for whom the key benefits of cough suppression are envisioned to outweigh the risks, and in whom an sufficient assessment in

The respiratory despair includes a discount during the responsiveness with the Mind stem respiratory facilities to the two increases in carbon dioxide stress also to electrical stimulation.g., amiodarone, quinidine) may possibly result in an increase in codeine plasma concentrations plus a lessen in Energetic metabolite morphine plasma focus which